Table 2 Demographic, clinical, genetic, and biomarker data of the study population

Gender (M/F)

15/25

35/45

0.513

Age (years)

62.2 ± 9.7

66.8 ± 9.2

0.013

MMSE

28.8 ± 1.9

18.9 ± 3.7

< 0.001

ApoE-ε4 (%)

–

53%

NA

Aβ42

 INNOTEST (pg/mL)

848 ± 232

479 ± 121

< 0.001

 Lumipulse (pg/mL)

726 ± 280

415 ± 126

< 0.001

Aβ40

 INNOTEST (pg/mL)

7999 ± 3975

7918 ± 3456

0.772

 Lumipulse (pg/mL)

7749 ± 3139

8474 ± 2847

0.105

t-Tau

 INNOTEST (pg/mL)

203 ± 92

598 ± 293

< 0.001

 Lumipulse (pg/mL)

217 ± 92

650 ± 291

< 0.001

p-Tau

 INNOTEST (pg/mL)

38.1 ± 13.0

75.3 ± 28.6

< 0.001

 Lumipulse (pg/mL)

30.6 ± 11.6

106.9 ± 48.0

< 0.001