Fig. 4
Retinal function in WT and 3×Tg-AD mice at 4, 8, 12, and 16 months of age, assessed by fERG, under photopic conditions. Main component values obtained in response to 9.49 cd.s/m2 light stimulus in WT (white bars) and 3×Tg-AD (black bars): a bcone amplitude, b base wave amplitude. The results are presented as mean ± SEM. **p < 0.01, ***p < 0.001 according to Student’s t test. nWT: at 4 months = 19, at 8 months = 19, at 12 months = 17, at 16 months = 17; n3×Tg-AD: at 4 months = 23, at 8 months = 23, at 12 months = 22, at 16 months = 22