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Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Retinal thinning of inner sub-layers is associated with cortical atrophy in a mouse model of Alzheimer’s disease: a longitudinal multimodal in vivo study

Fig. 1

Thickness of different retinal layers in WT (white bars) and 3×Tg-AD (black bars) mice at 4, 8, 12, and 16 months of age, based on in vivo OCT line scans. The thickness of retinal layers was measured using the InSight software. a Total retina, b GCL+IPL, c INL+OPL, d ONL, e IS+OS. The results are presented as mean ± SEM. *p < 0.05, ***p < 0.001, according to Student’s t test. nWT: at 4 months = 21, at 8 months = 19, at 12 months = 17, at 16 months = 17; n 3×Tg-AD: at 4 months = 22, at 8 months = 22, at 12 months = 22, at 16 months = 22

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