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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau

Fig. 3

Voxel-wise analysis of metabolic rescue in the Anle138 treatment group: Direct comparison between follow-up and baseline FDG-PET imaging by statistical parametric mapping of SUVR maps (upper row) as a region-independent analysis. Green coding (coronal slices upon an MRI template) indicates voxels with a significant increase during Anle138b treatment whereas red coding indicates voxels with a significant decrease (p < 0.01; unc; k > 20). SUVR PET images of an individual example are illustrated for baseline (middle row) and follow-up (lower row) time points and show a visually discernible increasing glucose metabolism during treatment

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