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Table 1 The expression levels of miRNAs related to synaptic proteins

From: Altered microRNAs related to synaptic function as potential plasma biomarkers for Alzheimer’s disease

Cohort 1

Cohort 2

 

HC

MCI

AD

HC

FTD

Cohort size

14

26

56

24

27

Men/women

7/7

10/16

15/41

11/13

17/10

Age (years)

68.29 ± 8.99

72.0 ± 8.49

77.77 ± 6.69

67.03 ± 5.05

68.87 ± 7.48

GDS

2.07 ± 0.26

3.15 ± 0.37

4.64 ± 1.02

1 ± 0

3.76 ± 0.99

MMSE

29.21 ± 1.05

26.92 ± 2.22

16.05 ± 7.23

28.5 ± 1.69

25.5 ± 3.76

  1. All data are shown as mean ± SD
  2. HC cognitively healthy controls, MCI mild cognitive impairment, AD Alzheimer’s disease, FTD frontotemporal dementia, MMSE Mini-Mental State Examination, GDS Global Deterioration Scale