Fig. 2From: Peripheral administration of human recombinant ApoJ/clusterin modulates brain beta-amyloid levels in APP23 miceSubchronic intravenous treatment of APP23 mice with human recombinant ApoJ (h-rApoJ). a Schematic timeline representing the experimental design of the study based on the subchronic administration of APP23 mice with rHDL-rApoJ nanodiscs, free rApoJ or saline. b Immunodetection (anti-h-ApoJ) of treatment samples before being intravenously infused. c Plasmatic levels of h-ApoJ in treated mice 30 min after the last administration detected by ELISA (N = 7/group). d Levels of h-ApoJ in brain homogenates from treated mice detected by ELISA (N = 7/group). e Immunofluorescent detection of h-ApoJ in paraffin-embedded brain sections. **p < 0.01; ***p < 0.001Back to article page