Fig. 3
From: 18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes
18F-flortaucipir in MAPT mutation carriers. a 18F-flortaucipir images and corresponding single-subject w-score maps in the following: (1) A 66-year-old V337 M carrier, MMSE 20, CSF Aβ negative. (2) A 68-year-old with R406W mutation, MMSE 16, PiB negative. (3) A 67-year-old P301L carrier, MMSE 5, PiB positive. (4) A 37-year-old S305I carrier, MMSE 4, PiB negative. (5) A 44-year-old IVS10 + 16 carrier, MMSE 30, PiB negative. (6) A 58-year-old IVS10 + 16 carrier, MMSE 27, PiB negative. b 18F-flortaucipir SUVR values for each pre-specified region of interest; horizontal bar denotes mean. L, left; NC, normal control; CDR-SB, Clinical Dementia Rating scale sum of boxes. *p ≤ 0.05