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Table 4 Logistic regression, modeling probability to progress to AD dementia within 3 and 5 years, respectively, as functions of age, female gender, and initial MMSE score

From: Erlangen Score as a tool to predict progression from mild cognitive impairment to dementia in Alzheimer’s disease

Covariate

Progression within 3 years (n = 116)

Progression within 5 years (n = 96)

Erlangen Score (reference category: Improbable AD)

 Possible AD

8.93 (1.02–78.04)*

3.90 (0.71–21.32)

 Probable AD

16.32 (1.96–136.2)*

16.77 (2.95–95.40)*

Age (years)

1.00 (0.95–1.06)

1.01 (0.95–1.08)

Female gender

1.24 (0.52–2.92)

0.94 (0.34–2.59)

MMSE

0.90 (0.80–1.02)

0.91 (0.77–1.08)

Log likelihood

−66.6

−50.8

  1. Odds ratios (95% confidence intervals) compared to the reference category (AD neurochemically improbable, i.e. Erlangen Score = 0 or 1)
  2. AD Alzheimer’s disease, MMSE Mini Mental State Examination, n number of patients in a given model
  3. *Statistical significance at p < 0.05 level, compared to the reference category