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Table 2 Variation of calculated Aβ concentrationsa between four parallel immunoprecipitations

From: A two-step immunoassay for the simultaneous assessment of Aβ38, Aβ40 and Aβ42 in human blood plasma supports the Aβ42/Aβ40 ratio as a promising biomarker candidate of Alzheimer’s disease

 

Aβ38 (pg/ml)

Aβ40 (pg/ml)

Aβ42 (pg/ml)

Mean

SD

%CV

Mean

SD

%CV

Mean

SD

%CV

Sample 1

54.08

2.38

4.40

207.22

32.06

15.47

20.38

1.45

7.12

Sample 2

54.04

3.39

6.27

216.78

26.08

12.03

23.45

1.94

8.26

Sample 3

55.44

1.19

2.15

201.50

4.50

2.23

20.12

0.43

2.12

Sample 4

46.37

2.01

4.34

162.46

8.15

5.01

18.60

1.29

6.93

Overall mean

52.48

2.24

4.29

196.99

17.70

8.69

20.64

1.28

6.11

  1. Aβ amyloid beta, %CV coefficient of variation, SD standard deviation
  2. aIndicated mean concentrations refer to averaged calculated concentrations (pg/ml) in diluted immunoprecipitation eluates without correction for 10-fold dilution before measurement with the Aβ triplex immunoassay
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Alzheimer's Research & Therapy

ISSN: 1758-9193