| sqrtWMH volume | sqrtLacunes |
---|
B | p Value | B | p Value |
---|
PiB(−) svMCI (n = 45) |
 Model 1 | 1.590 | 0.251 | 0.053 | 0.249 |
 Model 2 | 0.399 | 0.769 | 0.088 | 0.100 |
 Model 3 | 0.035 | 0.979 | 0.066 | 0.172 |
PiB(−) SVaD (n = 47) |
 Model 1 | −1.114 | 0.393 | −0.058 | 0.322 |
 Model 2 | −1.912 | 0.537 | −0.051 | 0.430 |
 Model 3 | −1.243 | 0.440 | −0.053 | 0.456 |
- Abbreviations: PiB Pittsburgh Compound B, sqrt Square root, svMCI Subcortical vascular mild cognitive impairment, SVaD Subcortical vascular dementia, WMH White matter hyperintensity
- Multiple linear regression was performed after controlling for the covariates as follows:
- Model 1: age, sex, ICV, and MMSE control
- Model 2: age, sex, ICV, MMSE, hypertension, diabetes, hyperlipidemia, and smoking control
- Model 3: age, sex, ICV, MMSE, hypertension, diabetes, hyperlipidemia, smoking, and global cortical thickness control