Primary outcome measure: | |
 • Neuropsychiatry Inventory (NPI) apathy/indifference domain score [42] | |
Secondary outcome measures: | |
 • Interpersonal Reactivity Index (IRI) empathic concern scale and total score [33] | |
 • Clinician’s Global Impression of Change (apathy) (m-CGIC) scores [43, 44] | |
 • Emotional facial expression recognition performance [17] | |
 • Revised Self-Monitoring Scale (RSMS) score [45] | |
 • NPI caregiver distress scores on NPI apathy/indifference scale and total caregiver distress scores [42] | |
 • Total NPI scores | |
 • Cambridge Behavioural Inventory [46] | |
 • Addenbrooke’s Cognitive Examination III [47] | |
 • Social Observation Checklist blinded central ratings of videotaped meals with patients and caregivers [35]. |