Table 2 Clinical signs and symptoms in primary progressive aphasia (PPA)
From: Single-word comprehension deficits in the nonfluent variant of primary progressive aphasia
Case | 2 | 4 | 13 | 16 | 17 | 18 | 21 | 3 | 12 | 14 | 19 | 20 | 1 | 5 | 6 | 8 | 10 | 7 | 9 | 11 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PPA variant | MV | MV | MV | MV | MV | MV | MV | NFV | NFV | NFV | NFV | NFV | SV | SV | SV | SV | SV | LV | LV | LV |
Hypomimetic facies | – | + | – | – | – | – | – | – | + | – | – | – | – | – | – | – | – | – | – | – |
Dysarthria | – | + | – | – | – | – | + | – | + | – | – | – | – | – | – | – | – | – | – | – |
Right-sided limb dystonia | – | + | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Right-sided extrapyramidal signs | – | + | + | – | – | – | – | – | + | + | + | + | – | – | – | – | – | – | – | – |
Alien limb | – | – | – | – | – | – | – | – | + | – | – | – | – | – | – | – | – | – | – | – |
Nuchal rigidity | – | + | + | – | – | – | + | – | – | – | – | – | – | – | – | – | – | – | – | – |
Reduced postural reflexes | – | + | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Falls | + | + | – | – | – | – | – | – | + | – | – | – | – | – | – | – | – | – | – | – |
Tremor | – | – | + | – | – | – | – | – | + | – | – | – | – | – | – | – | – | – | – | – |
Myoclonus | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Vertical gaze slowing or palsy | – | + | + | + | – | – | + | – | + | + | – | + | – | – | – | – | – | – | – | – |
Decrease in vertical optokinetic nystagmus | + | + | + | + | – | – | + | – | + | + | – | + | – | – | – | – | – | – | – | – |
Pyramidal signs | – | – | – | – | – | – | – | + | + | – | – | – | – | – | – | – | – | – | – | – |
Dysphagia | + | + | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Pseudobulbar affect | + | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Ideomotor apraxia | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |
Apraxia of eyelid closure | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – | – |