Table 1 Baseline characteristics of the study sample

Age, years

74.1 (69.5–78.5)

74.4 (69.1–78.2)

73.6 (69.8–78.7)

> 0.999

Female, n (%)

101 (39.1)

40 (33.6)

61 (43.9)

0.119

Education, years

16 (14–18)

16 (14–18)

16 (14–18)

0.469

APOE ε4 carrier, n (%)

176 (68.2)

78 (65.6)

98 (70.5)

0.473

 MMSE

27 (25–29)

28 (26–29)

26 (25–28)

< 0.001

 CDR SB

1.5 (1.0–2.5)

1.5 (1.0–2.0)

2.0 (1.0–2.5)

< 0.001

 ADAS-cog 11

11.8 (9.0–15.7)

10.7 (7.2–13.2)

13.0 (10.8–16.2)

< 0.001

 Aβ_1–42, mean ± SD, pg/mL

136.1 ± 25.7

136.7 ± 27.2

133.7 ± 25.0

0.345

 CSF t-tau, pg/mL^a

104.0 (77.0–148.5)

91.0 (68.0–133.0)

113.0 (84.0–153.0)

0.006

 CSF p-tau, pg/mL^b

41.0 (31.0–58.0)

37.0 (27.0–51.0)

45.0 (36.0–64.0)

< 0.001

 Tesla, n (%)

0.714

  1.5

143 (55.4)

64 (53.8)

79 (56.8)

  3.0

115 (44.6)

55 (46.2)

60 (43.2)

 MTA, n (%)

123 (47.7)

47 (39.5)

76 (54.7)

0.021

 PA, n (%)

174 (67.4)

65 (54.6)

109 (78.4)

<0.001

 Atrophy pattern, n (%)

<0.001

  No atrophy

51 (19.8)

39 (32.8)

12 (8.6)

  MTA only

33 (12.8)

15 (12.6)

18 (13.0)

  PA only

84 (32.6)

33 (27.7)

51 (36.7)

  Both MTA and PA

90 (34.9)

32 (26.9)

58 (41.7)