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Fig. 2 | Alzheimer's Research & Therapy

Fig. 2

From: Dietary arachidonic acid increases deleterious effects of amyloid-β oligomers on learning abilities and expression of AMPA receptors: putative role of the ACSL4-cPLA2 balance

Fig. 2

Modifications of erythrocyte fatty acid composition by oleic acid-enriched (OLE) and arachidonic acid-enriched (ARA) diets. Mice were fed a standard diet for 2 weeks before the experiments. Blood samples were collected, and then two groups were fed the OLE or ARA diet for 12 weeks. Second blood samples were collected at the end of the 12th week. Fatty acid composition was measured by gas chromatography to evaluate the evolution of the fatty acid profiles between the beginning and the end of the experiments in the OLE- or ARA-fed mice. Saturated fatty acids (a), monounsaturated fatty acids (b), polyunsaturated ω-6 fatty acids (c), and polyunsaturated ω-3 fatty acids (d) were measured. * p < 0.05, ** p < 0.01, *** p < 0.001, comparison of measures at weeks 0 and 12 in a diet group (OLE or ARA). # p < 0.05, ## p < 0.01, ### p < 0.001, comparison between OLE- and ARA-fed mice at week 12. n = 10 in each diet group (ARA or OLE)

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