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Table 4 Sensitivity analyses for risk of head injuries (n = 3838) and brain injuries (n = 1914) associated with antidepressant use in case-crossover design

From: Risk of head and traumatic brain injuries associated with antidepressant use among community-dwelling persons with Alzheimer’s disease: a nationwide matched cohort study

 

Unadjusted OR (95% CI)

Adjusted OR (95% CI)a

Case window 1–14 days before the head injury

 Control window 30–45 days before

1.77 (1.13–2.77)

1.71 (1.09–2.68)

 Control window 60–74 days before

1.67 (1.19–2.34)

1.64 (1.17–2.30)

 Control window 120–134 days before

2.04 (1.55–2.70)

2.04 (1.55–2.70)

Case window 1–14 days before the traumatic brain injury

 Control window 30–45 days before

1.53 (0.83–2.82)

1.46 (0.79–2.70)

 Control window 60–74 days before

1.36 (0.85–2.16)

1.33 (0.83–2.11)

 Control window 120–134 days before

1.84 (1.24–2.73)

1.81 (1.22–2.69)

  1. aAdjusted for time-dependent use of benzodiazepines and related drugs, antipsychotics, and opiods
  2. CI confidence interval, OR odds ratio