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Table 3 Beta values for predictors of neuropsychological test scores, with model F and R 2 values using RSI and DTI metrics

From: Sensitivity of restriction spectrum imaging to memory and neuropathology in Alzheimer’s disease

 

Regressor

Beta

F value*

R 2

DRS

Arcuate ND

Hippocampus IF

0.64

–0.31

16.01

0.62

LMI

Entorhinal IF

Arcuate FA

–0.53

0.27

6.64

0.64

LMD

Entorhinal IF

Arcuate FA

–0.61

0.23

8.74

0.69

CVLT- SFR

Entorhinal IF

Arcuate ND

–0.45

0.34

11.47

0.75

CVLT- LFR

Entorhinal IF

Arcuate ND

–0.58

0.28

16.63

0.81

CERAD - DR

Entorhinal IF

IFOF FA

Fornix FA

–0.49

0.33

0.25

16.44

0.82

  1. Values corrected for age, sex, and education
  2. *All regression models significant at p < 0.001
  3. CERAD-DR Consortium to Establish a Registry for Alzheimer’s Disease delayed recall, CVLT-LFR California Verbal Learning Test long delay free recall, CVLT-SFR California Verbal Learning Test short delay free recall, DRS Dementia Rating Scale, DTI diffusion tensor imaging, FA fractional anisotropy, IF isotropic free water diffusion, IFOF inferior fronto-occipital fasciculus, LMI Logical Memory immediate, LMD Logical Memory delayed, ND neurite density, RSI restriction spectrum imaging