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Fig. 5 | Alzheimer's Research & Therapy

Fig. 5

From: A vaccine with Aβ oligomer-specific mimotope attenuates cognitive deficits and brain pathologies in transgenic mice with Alzheimer’s disease

Fig. 5

EBY100-L2 (AOE1) immunization decreased β-amyloid peptide (Aβ) deposits in the brains of Alzheimer’s disease (AD) mice. The plaques in the mouse brains were detected by thioflavin S (ThS) staining (a) and immunohistochemistry (IHC) using 4G8 (b), and the number of plaques in the brain sections stained by ThS staining (c) and IHC (d) was quantified using IpWin5 software (compared with AD control, *p < 0.05, **p < 0.01). WT Wild type

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Alzheimer's Research & Therapy

ISSN: 1758-9193