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Table 4 Concordance (kappa) between positron emission tomography and cerebrospinal fluid profiles in the cross-sectional and longitudinal cohorts

From: Comparison of CSF markers and semi-quantitative amyloid PET in Alzheimer’s disease diagnosis and in cognitive impairment prognosis using the ADNI-2 database

 

1–42

Tau

p-Tau181

p-Tau/Aβ

Cross-sectional cohort

 SUVr (pons)

0.82

0.60

0.57

0.74

 SUVr (crb)

0.81

0.60

0.60

0.75

 SUVr (comp)

0.84

0.61

0.59

0.75

Longitudinal cohort

 SUVr (pons)

0.80

0.67

0.70

0.79

 SUVr (crb)

0.78

0.65

0.69

0.81

 SUVr (comp)

0.83

0.67

0.69

0.81

  1. Abbreviations: Aβ Amyloid-β1–42, p-tau Phosphorylated tau, SUVr Standardised uptake value ratio, Pons Pontine, crb Cerebellar, comp Composite