Table 1 Baseline demographics, apolipoprotein E status and cerebrospinal fluid markers in the cross-sectional population by baseline status

Male sex

77 (49%)

204 (52%)

72 (58%)

Age, years

74 ± 6

72 ± 7^a

75 ± 8

ApoE4 carriers

42 (27%)

186 (47%)^b

82 (66%)^c

 GDS

0.7 ± 1.1

1.4 ± 1.4^b

1.7 ± 14^c

 MMSE

29 ± 1

27 ± 3^b

23 ± 2^c

 CDR 0

157 (100%)

96 (24%)^b

0^c

 CDR 0.5

0

299 (76%)^a

53 (43%)^c

 CDR ≥1

0

1 (0.3%)

71 (57%)^c

 ADAS-cog

9 ± 5

16 ± 10^b

31 ± 8^c

 Aβ_1–42, ng/L

196 ± 50

175 ± 53^b

137 ± 38^c

 Tau, ng/L

67 ± 34

88 ± 54^b

133 ± 65^c

 p-Tau₁₈₁, ng/L

33 ± 16

43 ± 26^b

60 ± 35^c

 p-Tau₁₈₁/Aβ_1–42

0.19 ± 0.13

0.29 ± 0.24^b

0.48 ± 0.32^c