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Table 2 Baseline neuropsychological data

From: Memory is preserved in older adults taking AT1 receptor blockers

Neuropsychological test

Total (n = 1586)

Normotensive (n = 782)

HTN-ARBs (n = 183)

HTN-Other (n = 621)

F-Value

p Value

Memory

 LM Immediate Recall

10.6 (4.3)

10.7 (4.4)

10.9 (4.3)

10.4 (4.2)

0.269

0.764

 LM Delayed Recall

8.5 (5.0)

8.6 (5.1)

9.2 (5.0)

8.3 (4.8)

1.987

0.137

 RAVLT Immediate Recall

38.2 (11.6)

39.6 (11.8)

38.1 (11.8)

36.5 (11.1)

4.986

0.007

 RAVLT Delayed Recall

5.3 (4.3)

5.8 (4.4)

5.5 (4.4)

4.5 (3.9)

9.642

<0.001

 RAVLT Recognition

11.4 (3.3)

11.7 (3.2)

11.7 (3.1)

11.0 (3.5)

5.692

0.003

Attention/executive function

 Digit Span forward score

8.4 (2.0)

8.5 (1.9)

8.1 (2.2)

8.4 (2.1)

1.100

0.402

 Digit Span forward span

6.6 (1.1)

6.7 (1.0)

6.5 (1.1)

6.6 (1.1)

0.953

0.386

 Digit Span backward score

6.5 (2.1)

6.6 (2.2)

6.5 (2.1)

6.4 (2.1)

0.121

0.886

 Digit Span backward span

4.8 (1.2)

4.8 (1.2)

4.7 (1.1)

4.7 (1.2)

0.021

0.979

 Trail Making Test A scorea

1.56 (0.16)

1.53 (0.15)

1.58 (0.16)

1.58 (0.16)

8.363

<0.001

 Trail Making Test B scorea

1.97 (0.21)

1.94 (0.21)

1.98 (0.20)

2.00 (0.21)

3.900

0.020

Language

 Animal Fluency

18.4 (5.5)

18.7 (5.4)

18.4 (5.3)

18.0 (5.7)

0.173

0.841

 Vegetable Fluency

12.2 (4.1)

12.3 (3.9)

12.2 (4.2)

12.1 (4.3)

0.206

0.814

 BNTa

0.48 (0.33)

0.47 (0.33)

0.47 (0.33)

0.51 (0.33)

1.385

0.251

  1. Abbreviations: BNT Boston Naming Test, HTN-ARBs Participants who took angiotensin II receptor blockers, HTN-Other Participants who took other antihypertensive drugs that were not angiotensin II receptor blockers, LM Logical Memory, RAVLT Rey Auditory Verbal Learning Test
  2. Data are summarized as mean (SD), unless otherwise indicated. All scores were corrected for age, sex, education level, BMI, and apolipoprotein ε4 allele carrier status. Significant differences (p < 0.05) among medication groups are indicated by boldface type
  3. aScores were log-transformed and are presented to two decimal places