From: The effects of different familial Alzheimer’s disease mutations on APP processing in vivo
All MC (n = 19) | APPswe (n = 9) | APParc (n = 4) | PSEN1 (n = 6) | NC (n = 17) | |
---|---|---|---|---|---|
Age (SD) | 46.7 (11.9) | 51.2 (12.1) | 50 (6.6) | 33.7 (7.0) | 47.8 (10.2) |
Years to onset (SD) | −7.7 (12.3) | −1.8 (12.1) | −7 (6.6) | −21.3 (7.0) | −6.9 (9.9) |
ApoE ε4 carrier | 9/19 | 5/9 | 1/4 | 3/6 | 7/17 |
Normal cognition | 13/19 | 4/9 | 4/4 | 5/6 | 17/17 |
MCI | 3 | 2 | - | 1 | - |
AD | 3 | 3 | - | - | - |