Skip to main content

Table 3 Number of subjects of subsample between 2001 and 2007 according to diagnosis at baseline, outcome at follow-up, and cerebrospinal fluid β-amyloid 1–42 cutoff score

From: Unbiased estimates of cerebrospinal fluid β-amyloid 1–42 cutoffs in a large memory clinic population

 

Total group (n = 688)

CSF Aβ42 cutoff <550 pg/ml

CSF Aβ 42 cutoff <615 pg/ml

AD-type dementia, n (%)

288 (42)

236 (82)

255 (89)

Non-AD-type dementia, n (%)

143 (21)

49 (34)

55 (38)

SCD with follow-up available

 Converted to AD-type dementia, n (%)

7 (7)

5 (71)

6 (86)

 Not converted to AD-type dementia, n (%)

91 (93)

16 (18)

20 (22)

MCI with follow-up available

 Converted to AD-type dementia, n (%)

69 (53)

53 (77)

60 (87)

 Not converted to AD-type dementia, n (%)

60 (47)

16 (27)

26 (43)

  1. Data are from the subsample of patients seen between 2001 and 2007. For this time period, the cutoff for CSF Aβ 42 determined with Gaussian mixture modeling was 615 pg/ml
  2. Abbreviations: CSF Cerebrospinal fluid, 42 Amyloid-β 1–42, SCD Subjective cognitive decline, MCI Mild cognitive impairment, AD Alzheimer’s disease