From: Characterization of FRM-36143 as a new γ-secretase modulator for the potential treatment of familial Alzheimer’s disease
DMSO
FRM-36143
p value
Aβtotal
4925 ± 185
5130 ± 92
0.161
Aβ38
750 ± 62
1548 ± 39
4.8E-05
Aβ40
4021 ± 132
3477 ± 120
6.2E-03
Aβ42
154 ± 2
105 ± 2
6.5E-06