Fig. 8From: Characterization of FRM-36143 as a new γ-secretase modulator for the potential treatment of familial Alzheimer’s diseaseShort Aβ peptides slow down aggregation of Aβ42 in vitro. Co-incubation of the shorter peptides Aβ37 or Aβ38 with Aβ42 in a ratio of 1:10 reduces aggregation of Aβ42 by more than threefold after 18 h under the assay conditions. Aβ37 and Aβ38 do not aggregate on their own. Data represent mean ± SEM of two experiments run in triplicateBack to article page