IADL | PSMS | |||||
---|---|---|---|---|---|---|
Significant predictors in final mixed modelsa | β | 95 % CI | p | β | 95 % CI | p |
Percentage of variance accounted for, all fixed terms | 56.0 %, p <0.001 | 39.9 %, p <0.001 | ||||
Fixed terms | ||||||
Intercept | 2.375 | −3.349, 8.099 | 0.414 | 4.844 | 2.154, 7.534 | <0.001 |
Time in months from baseline | 0.515 | 0.407, 0.623 | <0.001 | 0.188 | 0.162, 0.213 | <0.001 |
Baseline assessment score | 1.431 | 0.926, 1.936 | <0.001 | 0.900 | 0.789, 1.011 | <0.001 |
Baseline assessment score2 | −0.016 | −0.029, −0.003 | 0.019 | ns | ||
Time in months × baseline assessment score | −0.013 | −0.017, −0.008 | <0.001 | ns | ||
Time in months2 × baseline assessment score | −0.0001 | −0.0002, −0.00002 | 0.010 | ns | ||
Background variables | ||||||
MMSE score at baseline | −0.195 | −0.374, −0.016 | 0.033 | −0.203 | −0.339, −0.067 | 0.004 |
ChEI doseb | −0.025 | −0.048, −0.002 | 0.037 | −0.019 | −0.035, −0.003 | 0.021 |
Random terms (variance) | ||||||
Intercept | 5.089 | 3.832, 6.757 | <0.001 | 1.762 | 1.048, 2.963 | <0.001 |
Time in months | 0.008 | 0.005, 0.012 | <0.001 | 0.017 | 0.013, 0.024 | <0.001 |