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Figure 1 | Alzheimer's Research & Therapy

Figure 1

From: Cumulative, additive benefits of memantine-donepezil combination over component monotherapies in moderate to severe Alzheimer’s dementia: a pooled area under the curve analysis

Figure 1

Cognition (SIB): Snapshot and AUC analysis a . aIn panels A and B, statistical comparisons are made between groups; in C and D, statistical comparisons are made with respect to no change from baseline (zero change from baseline) and zero AUC, respectively. bAUC values corrected for interval duration (four or six weeks). *P <0.05 **P <0.01 ***P <0.001. AUC, area under the curve; LS, least squares; PBO, placebo; PBO-DON, placebo added to background donepezil treatment; SE, standard error of the mean; SIB, Severe Impairment Battery.

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