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Table 8 Incidence of arrhythmic events (SAS)

From: Long-term donepezil use for dementia with Lewy bodies: results from an open-label extension of Phase III trial

AE

PLA-DON10

DON5-DON10

DON10-DON10

DON-DON10 a

( n =37)

( n =47)

( n =49)

( n =96)

Subjects with any arrhythmic events, n (%)

3 (8.1)

4 (8.5)

5 (10.2)

9 (9.4)

Atrioventricular block

0

0

2 (4.1)

2 (2.1)

Palpitations

0

1 (2.1)

0

1 (1.0)

Sinus bradycardia

0

1 (2.1)

1 (2.0)

2 (2.1)

Supraventricular extrasystoles

0

1 (2.1)

0

1 (1.0)

Ventricular extrasystoles

0

0

1 (2.0)

1 (1.0)

Electrocardiogram QT prolonged

0

1 (2.1)

0

1 (1.0)

Loss of consciousness

2 (5.4)

0

1 (2.0)

1 (1.0)

Syncope

1 (2.7)

0

0

0

  1. SAS, safety analysis set; AE, adverse event.
  2. aDON5-DON10 and DON10-DON10 groups.