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Figure 9 | Alzheimer's Research & Therapy

Figure 9

From: Evaluating the relationship between amyloid-β and α-synuclein phosphorylated at Ser129 in dementia with Lewy bodies and Parkinson’s disease

Figure 9

Percentage of insoluble α-syn phosphorylated at Ser129 after exposure of SH-SY5Y cells to aggregated or soluble Aβ1-42 and Aβ1-40. The percentage of insoluble α-syn that was phosphorylated at Ser129 was significantly increased after 24 hours exposure of the cells to 10 μM aggregated Aβ1-42 (P = 0.009). Ser129 phosphorylation was also higher after exposure to soluble 10 μM Aβ1-42 and aggregated 10 μM Aβ1-40 but the increases did not reach significance. Aβ, amyloid-β.

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