Figure 6

Percentage of insoluble α-syn phosphorylated at Ser129. Box-and-whisker plots indicate the full range, interquartile range and median value in each group. The percentage of insoluble α-syn phosphorylated at Ser129 was significantly higher in PDD than controls in all regions and in DLB in regions except the midfrontal cortex. In addition, the percentage was significantly higher in PDD than PDND in the midfrontal and parahippocampal cortex, and in DLB than PDND in the cingulate cortex. In the thalamus and parahippocampal cortex, the percentage of insoluble α-syn phosphorylated at Ser129 was significantly higher in PDND than controls. DLB, dementia with Lewy bodies; PDD, Parkinson’s disease with dementia; PDND, Parkinson’s disease without dementia; α-syn, α-synuclein.