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Table 4 Mean (± SEM) scores on neuropsychological, neuropsychiatric and functional measures in the CBS and VHF-DLB groups

From: Differentiating between visual hallucination-free dementia with Lewy bodies and corticobasal syndrome on the basis of neuropsychology and perfusion single-photon emission computed tomography

Psychometric measures CBS (number) VHF-DLB (number)
General cognition   
MMSE/30 (number =59) 21.7 ± 1.2 (31) 22.1 ± 1.1 (28)
Clock Drawing Test/10 (number =26) 6.9 ± 0.8 (9) 7.7 ± 0.6 (17)
NART/127.8 (number =38) 107.5 ± 1.9 (19) 108.4 ± 2.1 (19)
Raven’s Progressive Matrices (number =40) 21.9 ± 1.6 (22) 21.2 ± 1.3 (18)
DRS/144 (number =53) 113.5 ± 4.1 (26) 114.6 ± 3.7 (27)
Memory   
CVLT Long Delay Free Recall/16 (number =46)a 6.6 ± 0.6 (21) 2.4 ± 0.5 (25)
CVLT Long Delay Cued Recall/16 (number =46)a 7.4 ± 0.6 (21) 3.9 ± 0.5 (25)
Delayed Visual Reproduction /41 (number =40b 10.5 ± 2.3 (19) 4.2 ± 1.2 (21)
Language   
WAB total/100 (number =38) 85.7 ± 2.5 (23) 86.5 ± 2.2 (15)
Boston Naming/30 (number =47) 24.0 ± 1.0 (22) 22.5 ± 1.1 (25)
Semantic Fluency/20 (number =53) 9.8 ± 1.2 (26) 10.3 ± 1.0 (27)
Praxis   
WAB praxis/60 (n =48) 53.2 ± 1.6 (27) 55.6 ± 0.6 (21)
Attention and working memory   
Digit span - forward/12 (number =50) 7.0 ± 0.6 (23) 6.8 ± 0.5 (27)
Digit span - backward/12 (number =50) 4.6 ± 0.6 (23) 4.3 ± 0.5 (27)
Visuospatial abilities   
Rey Osterieth Complex Figure/36 (number =45) 17.0 ± 3.0 (20) 18.5 ± 2.3 (25)
Benton Line Orientation /30 (number =44) 13.2 ± 2.4 (21) 13.4 ± 2.3 (23)
Executive functions   
Phonemic (FAS) fluency (number =47) 19.1 ± 2.7 (21) 22.1 ± 3.2 (26)
Trail Making Test A (time in seconds) (number =42) 108.7 ± 14.7 (19) 101.4 ± 11.5 (23)
Trail Making Test B (time in seconds) (number =31) 214.5 ± 39.7 (13) 193.6 ± 20.9 (18)
WCST categories/6 (number =44) (22) (22)
Categories 0 to 1: Counts (%) 11 (50%) 17 (77%)
Categories 2 to 4: Counts (%) 11 (50%) 5 (23%)
WCST perseverative errors (number =44) 11.7 ± 2.9 (22) 19.8 ± 3.4 (22)
Neuropsychiatric features   
Cornell Depression (number =54) 22.8 ± 2.6 (30) 16.0 ± 2.7 (24)
Neuropsychiatric Inventory/144 (number =55) 12.1 ± 2.5 (29) 10.5 ± 2.4 (26)
Functional measures   
DAD (%) (number =57) 68.8 ± 5.7 (30) 78.9 ± 4.1 (27)
  1. aP <0.005; bP <0.05. The number of patients tested is listed next to individual measures. Missing data are secondary to the inability of the patient to complete the test. CBS, corticobasal syndrome; CVLT, California Verbal Learning Test; DAD, Disability Assessment Scale for Dementia; DRS, Mattis Dementia Rating Scale; FAS, F-, A-, and S-phonemic fluency; MMSE, Folstein’s Mini-Mental State Exam; NART, National Adult Reading Test; SEM, standard error of the mean; VHF-DLB, visual hallucination-free dementia with Lewy bodies; WAB, Western Aphasia Battery; WCST, Wisconsin Card Sort Test.
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