Association between Hoehn and Yahr, Mini-Mental State Examination, age, and clinical syndrome predominance and diagnostic effectiveness of ioflupane I 123 injection (DaTSCANTM) in subjects with clinically uncertain parkinsonian syndromes

Table 1 Subject subgroup relationship to 1-year clinical diagnosis (standard of truth) and ioflupane [ ¹²³ I] imaging results ( n = 92)

Subjects with CUPS		Subgroup: H&Y stage			Subgroup: MMSE score			Subgroup: age of subjects at baseline			Subgroup: clinical syndrome predominance at baseline^a
1-year clinical diagnosis	Ioflupane [¹²³I] imaging results	<2	≥2	Total	<29	≥29	Total	<68 years	≥68 years	Total	TD	BRP dominant	B	Total
PS	Normal	2	1	3	1	2	3	2	1	3	0	2	1	3
	Abnormal	26	20	46	19	27	46	15	31	46	10	17	19	46
Non-PS	Normal	20	21	41	16	25	41	15	26	41	25	4	12	41
	Abnormal	0	2	2	1	1	2	2	0	2	0	2	0	2
Total		48	44	92	37	55	92	34	58	92	35	25	32	92

Data presented as numbers. B, balanced; BRP, bradykinesia, rigidity, postural instability; CUPS, clinically uncertain parkinsonian syndrome; H&Y, Hoehn and Yahr; MMSE, Mini-Mental State Examination; PS, parkinsonian syndrome; TD, tremor dominant. ^aTD, tremor score > BRP; BRP dominant, BRP > tremor score; B, maximal score of BRP = tremor score. Scores for these motor signs were 1 for none, 2 for possible, and 3 for definite.

ISSN: 1758-9193