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Table 1 Demographics and baseline characteristics in the intention-to-treat populationa

From: Analyzing the impact of 23 mg/day donepezil on language dysfunction in moderate to severe Alzheimer's disease

Characteristics

Donepezil 23 mg/day

Donepezil 10 mg/day

Age, years

  

Number of patients

909

462

Mean (±SD)

73.8 (8.48)

73.8 (8.55)

Gender

  

Number of patients

909

462

Males, n (%)

335 (36.9%)

175 (37.9%)

Females, n (%)

574 (63.1%)

287 (62.1%)

MMSE

  

Number of patients

908

462

Mean (±SD)

13.1 (4.99)

13.1 (4.72)

ADCS-ADL-sev total

  

Number of patients

908

461

Mean (±SD)

34.1 (10.88)

34.5 (11.19)

SIB

  

Number of patients

907

462

Mean (±SD)

74.2 (17.58)

75.6 (16.28)

CIBIS-plus

  

Number of patients

904

461

Mean (±SD)

4.42 (0.85)

4.38 (0.89)

Concomitant memantine use

  

Number of patients

909

462

Using memantine, n (%)

338 (37.2)

163 (35.3)

  1. aMMSE = Mini-Mental State Examination; ADCS-ADL-sev = Alzheimer's Disease Cooperative Study-Activities of Daily Living inventory, severe version; SIB = Severe Impairment Battery; CIBIS-plus = Clinician's Interview-Based Impression of Severity-plus caregiver input; SD = standard deviation.
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Alzheimer's Research & Therapy

ISSN: 1758-9193