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Table 2 Logistic regression models illustrating the odds of all-cause dementia, Alzheimer's disease and vascular dementia (95% confidence intervals) by vascular conditions, diabetes and APOE genotype

From: Vascular health, diabetes, APOE and dementia: the Aging, Demographics, and Memory Study

 

All-cause dementia

Alzheimer's disease

Vascular dementia

 

Basic adjusted models*

Fully adjusted models†

Basic adjusted models*

Fully adjusted models†

Basic adjusted models*

Fully adjusted models‡

Hypertension

0.7 (0.4-1.2)

0.7 (0.4-1.2)

0.6 (0.4-1.1)

0.7 (0.4-1.2)

1.7 (0.6-5.0)

2.0 (0.6-6.3)

Diabetes

0.9 (0.5-1.7)

1.1 (0.5-2.1)

0.6 (0.3-1.6)

0.7 (0.3-1.7)

0.8 (0.4-1.4)

0.5 (0.2-1.1)

Heart disease

1.5 (0.9-2.6)

1.4 (0.8-2.4)

1.4 (0.8-2.6)

1.5 (0.8-2.9)

2.2 (0.7-7.6)

2.6 (0.8-8.4)

Stroke

3.7 (2.2-6.2)

3.7 (2.0-6.9)

2.4 (1.5-3.9)

2.3 (1.3-4.0)

§

§

APOE ε4

2.5 (1.7-3.9)

2.8 (1.7-4.5)

2.6 (1.5-4.6)

2.6 (1.5-4.8)

2.3 (1.0-5.2)

2.3 (1.1-5.1)

  1. Population weights are used to adjust for the sampling design. *Adjusted for age, sex, education, ethnicity, and Health and Retirement Study (HRS) wave. †Adjusted for age, sex, education, ethnicity, HRS wave, and all other variables in the table. ‡Adjusted for age, sex, education, ethnicity, HRS wave, and all other variables in the table excluding stroke. §Not examined as stroke is a central diagnostic criterion for vascular dementia [31]. APOE ε4, apolipoprotein ε4.