From: Platelet-activating factor antagonists enhance intracellular degradation of amyloid-β42 in neurons via regulation of cholesterol ester hydrolases
Concentration of Aβ42, nM
Cell extracts
DRMs
Lysosomes
Control
8.7 ± 0.7
8.4 ± 0.6
0.4 ± 0.2
Hexa-PAF
8.5 ± 1.2
2.5 ± 0.9a
3 ± 0.6b
Squalene
8.5 ± 0.9
8 ± 0.4
0.5 ± 0.2
Hexa-PAF + squalene
8.8 ± 0.6
2.8 ± 0.8a
3 ± 0.4b