Skip to main content
Figure 2 | Alzheimer's Research & Therapy

Figure 2

From: Photobiomodulation with near infrared light mitigates Alzheimer’s disease-related pathology in cerebral cortex – evidence from two transgenic mouse models

Figure 2

Effect of near-infrared light treatment on hyperphosphorylated tau and neurofibrillary tangles in the neocortex of K3 mice. (A), (B) Quantification of tau AT8 immunolabelling, based on average labelling intensity (A) and labelled area (B). All error bars indicate standard error of mean. *P < 0.05, **P < 0.01. (C), (D), (E) Representative photomicrographs of sections stained with Bielschowsky silver stain to demonstrate neurofibrillary tangles (NFTs). Arrows indicate axonal swellings and NFTs. (F), (G), (H) Representative micrographs of AT8 (red) labelling within neurons of the neocortex retrosplenial area. Nuclei were labelled with bisbenzimide (blue). Scale bars = 50 μm; scale in (E) applies to (C) and (D), scale in (H) applies to (F) and (G). NIr, near-infrared light; WT, wildtype.

Back to article page