Table 1 Summary of some recent multiplex Alzheimer's disease biomarker studies

Doecke et al. [41]

Multiplex panel: Human Discover MAP, version 1.0; RBM

151 multiplexed analytes

Watt et al. [47]

Copper immobilized metal affinity capture and SELDI

Three candidate biomarkers in blood

Ray et al. [40]

Filter based, arrayed sandwich-ELISA

Chemokines, growth factors, and inflammation markers

Zhang et al. [48]

Multidimensional LC in combination with one- and two-dimensional PAGE

Serum-based biomarkers

MALDI and ESI-MS

Inflammatory response mediators

ELISA multiplex platforms

Amyloid beta

Henkel et al. [49]

Anion exchange and reverse phase chromatography

12 high-abundance proteins from plasma

Choi et al. [50]

Two-dimensional PAGE, western blot, and MALDI-MS

Fibrinogen gamma chain and alpha1 antitrypsin

Lopez et al. [51]

Affinity chromatography, spin columns and MALDI-MS

Pattern of unidentified proteins in serum